Model: | MOS 131707-25-0 |
Brand Name: | MOSINTER |
CAS No.: | 131707-25-0 |
Molecular weight: | 531.89 |
Molecular formula: | C22H25BrN2O3S |
Arbidol CAS 131707-25-0
Description:
Abidol is a dual effect anti influenza virus drug developed by the former Soviet Pharmaceutical Chemistry
Research Center, which can simultaneously fight influenza A and B caused by influenza virus, and has antiviral
activity against other respiratory virus infections. It was first listed in Russia in 1993 to prevent and treat
influenza and other acute respiratory virus infections. The latest research shows that abidol can effectively
inhibit the new pneumonia coronavirus.
Specifications:
Test Items | Specification | Test Results |
Appearance | White powder | White powder |
Melting point | 125~127°C | Conforms |
Specific Rotation | +28°~+30° | +29° |
Acidity(PH) | 5.2~6.5 | 5.8~6.2 |
Water | 4.0%~5.5% | 5.00% |
Residue On Ignition | Not more than 0.1% | Conforms |
N.N – dimethylaniline | Comply with the standard | Conforms |
Phenolic Compounds | Comply with the standard | Conforms |
Related Substance | Comply with the standard | Conforms |
Assay | Between99.0~102.0% | 99.53% |
Conclusion | This batch is complies with USP 41 |
Application:
Abidol is suitable for the prevention and treatment of influenza A, influenza B, acute viral respiratory infection
and severe acute respiratory syndrome in adults and children, including bronchitis and pneumonia. The use of
abidol hydrochloride in the early stage after the onset of influenza can significantly shorten the duration of the
disease and reduce the severity of the symptoms. It has a significant effect on improving the symptoms of influenza
patients, such as cough, headache, fever, chills, sweating, sore throat, muscle pain, chemical book and fatigue, and
it is safe and suitable for clinical application. Usage and dosage: 100mg / capsule, oral, 2 capsules per time for children
and adults over 13 years old, 1 capsule per time for children aged 6-12 years old, and 50mg per time for children aged
2-6 years old. Treatment: 3 times a day for 3-5 days. Prevention: take once every three days for three weeks in the
epidemic period of influenza; take once a day for two weeks in high-risk groups contacting patients.
On February 4, 2020, Li Lanjuan, academician of Chinese Academy of engineering and member of the high level expert
group of the national health and Health Commission, said that according to the preliminary test, in vitro cell experiments
showed that abidol at 10-30 micromolar concentration, compared with the untreated control group, could effectively inhibit
the coronary virus up to 60 times, and significantly inhibit the pathological effect of the virus on cells.
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