Chloropromazine hydrochloride (CAS: 69-09-0)

Chemical property:White or milk white crystalline powder. The

melting point of 179-180 ℃ (179-180 ℃). Soluble in water, ethanol,

chloroform, insoluble in ether and benzene. Have led to wet, 5% aqueous

solution with a pH value of 4 to 5. Slight odor, taste very bitter. Easy oxidation

of this product, in the air or sunlight gradient is reddish brown.

Application:This product is representative of the command thiamethoxam medicine.

On the central nervous system, small doses have stable effect, large dose of continuous

use have antipsychotic effect, this product under the inhibition of the thalamus of the

temperature regulating center, the body temperature with environment temperature rise

and fall, cooperate with other medicine, the temperature fell below the normal body

temperature, reduced metabolism, says artificial hibernation. Mainly used for antipsychotic,

strengthen soporific, anesthetics, analgesics, and anticonvulsant effect. And can be used in

the town of vomiting and intractable hiccups vomit and cause artificial hibernation.

1. The treatment of mental illness: is used to control schizophrenia or other psychiatric excited

excitement, nervous, symptoms such as hallucinations, delusions, the symptoms of depression

and stupor curative effect is poorer.                  

2. Sickness: almost vomiting caused by various reasons, such as uremia, gastroenteritis, cancer,

the vomiting of pregnancy and medicine are all effective. Can also be used in the treatment of

intractable hiccups, but for motion sickness vomiting is invalid.                                               

3. Low temperature anesthesia and artificial hibernation: used for low temperature can prevent

shock occurred during anesthesia.                                                                         

4. Share, and analgesic pain for the treatment of terminal cancer patients.                         

5. Treatment of heart failure.                                                                       

6. Try to treat gigantism.

Method of manufacturing:By 2 – chloro phenothiazine [7] 92-39 – condensation, the salt.

In condensation reaction pot add 2 – chlorine phenothiazine and toluene, add sodium hydroxide,

mixing heating reflux, removing moisture, at 110 ℃ and 1 – chlorine – 3 – dimethylamino propane

toluene solution, the reactant decompression recycled toluene, a quick chlorpromazine, C17H19CIN2S,

50-53 – [3]. 2. As chlorpromazine and isopropyl alcohol salt will stir heated to 40 ℃, ventilation with

dry hydrogen chloride to pH4-5, namely into chlorpromazine hydrochloride salt.

Packing: 25 kilograms Paper barrel.