Model: | MOS 111358-88-4 |
Place of Origin: | Shandong,China (Mainland) |
Brand: | MOSINTER |
Melting Point: | 215-220℃ |
Boiling point: | 722.959°C at 760 mmHg |
Density: | 1.709g/cm3 |
Vapour pressure: | 0mmHg at 25°C |
Flashing point: | 391.031°C |
Lestaurtinib (CAS: 111358-88-4)
Item | Index |
Molecular Formula | C26H21N3O4 |
Molecular Weight | 439.469 |
Specification | CP/USP/EP |
Melting point | 215-220°C |
Lestaurtinib (rINN, codenamed CEP-701) is a tyrosine kinase inhibitor structurally related to staurosporine, and is being developed by Cephalon.
It is an inhibitor of FLT3, JAK2,TrkA, TrkB and TrkC.
Uses
It is undergoing research for the treatment of acute myelogenous leukemia (AML) and myeloproliferative disorders.
As of 2009, it is in Phase II clinical trials for AML and Phase II clinical trials for myeloproliferative disorders.
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