Paroxetine hydrochloride (paxil) is a phenylpiperidine compound,

developed by glaxosmithkline and marketed in 1991.

Usage:Paroxetine can inhibit the reabsorption of synaptosomes of

5- HT strongly and selectively, does not directly interfere with any

central neurotransmitter receptor. Used for depression, especially

anxiety and obsessive compulsive disorder. 

Paroxetine hydroehlchloride: C19H20FNO3;HCI.Tiny flake crystallization,

melting point 118 ℃.

Paroxetine Maleate Maleate: C19H20FNO3?C4H4O4.From ethanol, ethyl ether

crystallization, melting point of 136 ~ 138 ℃.[alpha] D – 87 ° (C = 5, ethanol).

Acute toxic LD50 mice (mg/kg) : 845 subcutaneous injection, 500 oral.