Model: | MOS 274693-27-5 |
Place of Origin: | Zhejiang,China (Mainland) |
Name: | TICAGRELOR |
CAS: | 274693-27-5 |
Molecular Formula: | C23H28F2N6O4S |
Molecular Weight: | 522.574 |
Content: | 98%min |
Density: | 1.67 |
Synonyms 1: | Azd 6140 |
Synonyms 2: | Unii-glh0314rvc |
Synonyms 3: | Ticagrelor(AR-C 126532XX |
Brand: | MOSINTER |
TICAGRELOR CAS 274693-27-5
icagrelor is a new kind of antiplatelet aggregation drug
Ticagrelor is used for the prevention of thrombotic events (for example stroke or heart attack)
in people with acute coronary syndrome or myocardial infarction with ST elevation. The drug
is combined with acetylsalicylic acid unless the latter is contraindicated. There is no high quality
evidence for the use of ticagrelor in non-ST elevation acute coronary syndrome.The FDA indication
for ticagrelor is reduction of the rate of cardiovascular death, myocardial infarction (MI), and stroke
in people with acute coronary syndrome or history of myocardial infarction.[citation needed]
AHA/ACC Guidelines (09/2014) state: “It is reasonable to choose ticagrelor over clopidogrel for
P2Y12 inhibition treatment in patients with NSTE-ACS treated with early invasive strategy
and/or coronary stenting”.
Ticagrelor was found to be comparable to acetylsalicylic acid in people with acute ischemic
stroke or transient ischemic attack.
Ticagrelor is a nucleoside analogue: the cyclopentane ring is similar to the sugar ribose, and the
nitrogen rich aromatic ring system resembles the nucleobase purine, giving the molecule an overall
similarity to adenosine. The substance has low solubility and low permeability under the
Biopharmaceutics Classification System.