Vitamin D2 CAS 50-14-6

Vitamin D2 (CAS: 50-14-6)

ITEM	SPECIFICATION	INDEX
Appearance	White powder, soluble in water	Complies
Differentiate	Positive reaction	Positive reaction
Particle Size	95% pass through sieve No.3	Complies
Loss on drying	≤ 13%	9.4%
Arsenic	≤ 0.0001%	Complies
Heavy metal	≤ 0.002%	Complies
Content	90.0% ~ 110.0% of label C28H44O content	101.0%

Ergocalciferol may be used as a vitamin D supplement, and a 2011 clinical guideline considered it to be

as effective as cholecalciferol (vitamin D3) which is produced naturally by the skin when exposed to

ultraviolet light. It is manufactured and marketed under various names, including Deltalin (Eli Lilly

and Company), Drisdol (Sanofi-Synthelabo) and Calcidol (Patrin Pharma).

Alfalfa (Medicago sativa subsp. sativa), shoot: 4.8 μg (192 IU) vitamin D2, 0.1 μg (4 IU) vitamin D3

Ergocalciferol is produced in fungi synthetically through irradiation of ergosterol.Human bioavailability

of vitamin D2 from vitamin D2-enhanced button mushrooms via UV-B irradiation is effective in improving

vitamin D status and not different from a vitamin D2 supplement. Vitamin D2 from UV-irradiated yeast baked

into bread is bioavailable. By visual assessment or using a chromometer, no significant discoloration of irradiated

mushrooms, as measured by the degree of “whiteness”, was observed.Claims that a normal serving of mushrooms

treated with ultraviolet light provides the equivalent of 3,500 International Units of vitamin D when exposed to

ultraviolet light after harvest have gained popular attention.

Research concerning efficacy of vitamin D2 and D3

Some preliminary studies indicate D3 is more potent, while others report equal efficacy. Both forms appear to have

similar efficacy in ameliorating rickets and reducing the incidence of falls in elderly patients.

The metabolism of each appears to be different, with the vitamin D binding protein possibly having greater affinity

for 25(OH)D3 than for 25(OH)D2, as shown in one study. Cholecalciferol (vitamin D3) is sensitive to UV radiation

and rapidly, but reversibly, forms other sterols which can further irreversibly convert to ergosterol.

Preliminary research

One study found low vitamin D2 levels in patients with Alzheimer’s disease, but this observational study did not

prove cause or effect related to ergocalciferol and vitamin D2 deficiency in the diet.

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